SAOTOME LAB | 小山工業高等専門学校 物質工学科

原著論文（英文）

[11] Design and Escherichia coli Expression of a Natively Folded Multi-Disulfide Bonded Influenza H1N1-PR8 Receptor-Binding Domain (RBD)
Thao Tu, Tharangani Rathnayaka, Toshiyo Kato, Kenji Mizutani, Tomonori Saotome, Keiichi Noguchi, Shun-ichi Kidokoro, Yutaka Kuroda
International Journal of Molecular Sciences 25(7) 3943-3943 2024年4月

[10] Direct Analysis of Mitochondrial Damage Caused by Misfolded/Destabilized Proteins
Jannatul Aklima, Sawaros Onchaiya, Tomonori Saotome, Punitha Velmurugan, Taihei Motoichi, Jannatul Naima, Yutaka Kuroda, Yoshihiro Ohta
International Journal of Molecular Sciences 23(17) 9881-9881 2022年8月

[9] Blocking PSD95‐PDZ3’s amyloidogenesis through point mutations that inhibit high‐temperature reversible oligomerization (RO)
Tomonori Saotome, Sawaros Onchaiya, Brindha Subbaian, Taichi Mezaki, Satoru Unzai, Keiichi Noguchi, Jose C. Martinez, Shun‐ichi Kidokoro, Yutaka Kuroda
The FEBS Journal 289(11) 3205-3216 2022年6月

[8] Reverse Engineering Analysis of the High-Temperature Reversible Oligomerization and Amyloidogenicity of PSD95-PDZ3.
Sawaros Onchaiya, Tomonori Saotome, Kenji Mizutani, Jose C Martinez, Jeremy R H Tame, Shun-Ichi Kidokoro, Yutaka Kuroda
Molecules (Basel, Switzerland) 27(9) 2022年4月

[7] EGFR extracellular domain III expressed in Escherichia coli with SEP tag shows improved biophysical and functional properties and generate anti-sera inhibiting cancer cell growth
Subbaian Brindha, Md Golam Kibria, Tomonori Saotome, Satoru Unzai, Yutaka Kuroda
Biochemical and Biophysical Research Communications 555(28) 121-127 2021年5月

[6] Solution structure of Gaussia Luciferase with five disulfide bonds and identification of a putative coelenterazine binding cavity by heteronuclear NMR
Nan Wu, Naohiro Kobayashi, Kengo Tsuda, Satoru Unzai, Tomonori Saotome, Yutaka Kuroda, Toshio Yamazaki
Scientific Reports 10(1) 20069 2020年11月

[5] Thermodynamic Analysis of Point Mutations Inhibiting High-Temperature Reversible Oligomerization of PDZ3
Tomonori Saotome, Taichi Mezaki, Subbaian Brindha, Satoru Unzai, Jose C Martinez, Shun-Ichi Kidokoro, Yutaka Kuroda
Biophysical Journal 119(7) 1391-1401 2020年8月

[4] Folding of the Ig-Like Domain of the Dengue Virus Envelope Protein Analyzed by High-Hydrostatic-Pressure NMR at a Residue-Level Resolution.
Tomonori Saotome, Maxime Doret, Manjiri Kulkarni, Yin-Shan Yang, Philippe Barthe, Yutaka Kuroda, Christian Roumestand
Biomolecules 9(8) E309 2019年7月

[3] Misfolding of a Single Disulfide Bonded Globular Protein into a Low-Solubility Species Conformationally and Biophysically Distinct from the Native One.
Tomonori Saotome, Toshio Yamazaki, Yutaka Kuroda
Biomolecules 9(6) E250 2019年6月

[2] Thermodynamics of the Thermal Denaturation of Acid Molten Globule State of Cytochrome c Indicate a Reversible High-Temperature Oligomerization Process
Shigeyoshi Nakamura, Tomonori Saotome, Akiko Nakazawa, Masao Fukuda, Yutaka Kuroda, Shun-ichi Kidokoro
Biochemistry 56(18) 2372-2378 2017年5月

[1] Unusual Reversible Oligomerization of Unfolded Dengue Envelope Protein Domain 3 at High Temperatures and Its Abolition by a Point Mutation
Tomonori Saotome, Shigeyoshi Nakamura, Mohammad M. Islam, Akiko Nakazawa, Mariano Dellarole, Fumio Arisaka, Shun-ichi Kidokoro, Yutaka Kuroda
Biochemistry 55(32) 4469-4475 2016年8月

総説論文（和文）

[1] 小型球状蛋白質の高温での可逆的なオリゴマー(RO)形成およびアミロイド線維の抑制
早乙女 友規
熱測定 50(3) 103-109 2023年7月